POLYMERIC MATERIALS AND MANUFACTURING IN MEDICINE

Academic Year 2023/2024 - Teacher: Gianluca CICALA

Expected Learning Outcomes

At the end of the course the student will be able to recognize the main classes of polymeric materials used in the medical field, identifying their structure and properties. Furthermore, they will understand the type of production processes depending on the type of object to be created and, through laboratory practice, they will have acquired the fundamentals of some testing and production techniques.

Course Structure

Frontal and Laboratory sessions

Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.

Required Prerequisites

The prerequisites are Chemistry and Physics. The course will provide basic knowledge where not present.

Attendance of Lessons

Attendance is considered compulsory. It being understood that extensions to this limit are in force for working students

Detailed Course Content

 

  1. Introduction to Materials Science (10 hours)
    1. Materials structure: basic concepts (2)
    2. Materials classification: Metals, Polymers, Ceramics and Composites. (3)
    3. Thermomechanical properties of Materials (5) (Stress and Strain, Tensile and Flexural testing, Tg and Tm, CTE)

 

2. Introduction to Materials used in Medicine (20 hours)

    1. Introduction to biomaterials science (2) (Classification, Surface interaction, Role of Water)
    2. Some examples of biomaterials used in medicine (18)

2.2.1        Titanium (artificial prosthesis)

2.2.2        Stainless steel (screw and jigs)

2.2.3        Zirconia (Dental application)

2.2.4        UHMWPE (artificial prosthesis)

2.2.5        PVC (tubing and )

2.2.6        PES (stent)

2.2.7        PCL (Scaffold)

2.2.8        PMMA (intraocular lens)

2.2.9        Fiber reinforced composites (external prosthesis and jigs)

2.2.10     Thermoset Resins (microfluidic)

 

  1. Manufacturing technologies used in medicine (15 hours)

 

    1. Polymer Extrusion and film blowing -> piping, suture and (sacche di sangue) (2)
    2. Injection Moulding -> stents and generic medical devices (1)
    3. Electrospinning -> scaffolds (3)
    4. Metal AM -> artificial prosthesis (3)
    5. Polymer AM -> scaffold and Invisalign (6)

 

  1. Laboratory practice (15 hours)
    1. Mechanical testing (2) (Testing of a Metallic and Plastic Specimens; DMA and CTE testing)
    2. Polymer Additive Manufacturing (7)
    3. Polymer extrusion (1)
    4. Composite Manufacturing (4)
    5. Electrospinning (1)

Textbook Information

The texts below are recommended for consultation. During the course, slides and articles useful for preparing for the exam will be provided.
1) W. R. Wagner et al Biomaterials Science. An Introduction to Materials in Medicine. Academic Press Elsiever
2)
Tim A. Osswald  Science of Polymers for Engineers. Hanser 

Course Planning

 SubjectsText References
1Materials Science : an introduttivoW. R. Wagner et al Biomaterials Science. An Introduction to Materials in Medicine. Academic Press Elsiever
2An introduction to Materials used in MedicineW. R. Wagner et al Biomaterials Science. An Introduction to Materials in Medicine. Academic Press Elsiever
3Manufacturing techniques used in medicineW. R. Wagner et al Biomaterials Science. An Introduction to Materials in Medicine. Academic Press Elsiever
4Laboratory PracticeW. R. Wagner et al Biomaterials Science. An Introduction to Materials in Medicine. Academic Press Elsiever

Learning Assessment

Learning Assessment Procedures

Learning assessment will be based on the completion of conceptual tests (questions to multiple and open answer), realization of practical experiences and case studies; discussion final oral. 


To guarantee equal opportunities and in compliance with current laws, students can request a meeting in order to plan any compensatory and/or dispensatory measure, according to the educational goals and specific needs. In this case, it is advisable to contact the CInAP (Centre for Active and Participated Integration - Services for Disabilities and/or SLD) professor of the Department where the Degree Course is included.


To guarantee equal opportunities and in compliance with current laws, students can request a meeting in order to plan any compensatory and/or dispensatory measure, according to the educational goals and specific needs. In this case, it is advisable to contact the CInAP (Centre for Active and Participated Integration - Services for Disabilities and/or SLD) professor of the Department where the Degree Course is included

Examples of frequently asked questions and / or exercises

Why is UHMPE used in knee replacements?


Which criterion can be used when choosing a polymer for application in the dental field?



How do you identify the printing time in an FDM machine?
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